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Summary Retatrutide, a triple agonist now in phase 3 trials, has the potential to become the most effective pharmacological treatment for obesity while also offering substantial benefits in T2D management and other cardiometabolic risk factors

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The normal course of untreated hyperuricemia, leading to progressive urate crystal deposition, begins with uric acid urolithiasis (urate kidney stones) and progresses to acute gouty arthritis, then intercritical gout and chronic tophaceous gout

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These nodules can be solitary or multiple, filled with fluid (cystic), or solid

The post says to raise it with the provider, who can adjust the protocol safely, rather than interrupting treatment unilaterally